Is berberine good for liver. NAFLD involves an extensive array of clinical conditions.
Is berberine good for liver For instance, research published in the World Journal of Hepatology suggests that berberine can help protect the liver from injury and fibrosis. The liver then stores, filters, and if necessary, detoxifies the contents and sends clean nutrients to the rest of the body. Berberine was found to inhibit the growth of canine mammary gland carcinoma cells in vitro. This adverse effect may be associated with the activation of unfolded protein response and mTOR. Effects of Berberine on Liver Enzymes Jan 21, 2025 · This relationship is called the gut-liver axis. Mar 30, 2024 · Some of the proposed benefits of berberine include reducing blood sugar, increasing cardiovascular health, and promoting weight loss. pylori infection and colonic adenoma prevention. According to their findings, berberine helped improve several liver health checks in NAFLD patients, like: Liver enzyme tests (AST, ALT, GGT): These enzymes are indicators of liver damage. However, it is important to use berberine responsibly, adhering to recommended dosages and consulting healthcare professionals when necessary. Therefore, interference with important hepatic metabolic pathways can be expected, however, up to now no extensive studies have Liver diseases are life-threatening illnesses and are the major cause of mortality and morbidity worldwide. It wasn’t until she started noticing a difference on the scale that she learned from a Google search that berberine could also aid in weight loss. Skin conditions Mar 14, 2022 · Berberine has, for thousands of years, been used to treat an enormous range of conditions, including eye, mouth and ear infections; skin irritations; wound healing; fever; microbial pathogens; digestive and respiratory diseases to name a few. In conclusion, this pilot study indicates that berberine is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism. However, more clinical randomized controlled trials with high quality are needed for further verification of berberine’s efficacy. These studies have enriched the understanding of berberine in the treatment of liver disease. However, hepatopathy morbidity and mortality are increasing year by year around the world, which become a major public health problem. Nov 13, 2023 · Then, in March, after hearing about the supplement berberine and how it could potentially help improve liver health, she decided to start taking 500 mg three times a day, with her meals. gov/28543822/ Therapeutic effects of berberine (BBR) on liver cirrhosis are associated with lipid metabolism and intestinal flora. Research on Berberine and Liver Health Jan 5, 2021 · A large amount of evidence has shown that berberine has a good protective effect on liver involving complex action mechanisms. Berberine was every bit as effective as the prescription drugs. Berberine is a type of alkaloid, which gives it a yellow color if you ever see it in powder form. Aug 4, 2024 · The liver is a vital organ that plays a crucial role in our overall health and well-being. Individuals taking medications such as anticoagulants or those prescribed for diabetes should consult their healthcare provider before starting Nov 30, 2023 · 4. As a result, people with diabetes may find that berberine helps lower their Feb 7, 2024 · In fact, berberine can actually help improve liver function and may be beneficial for treating non-alcoholic fatty liver disease (NAFLD). 2013). Pi*Z transgenic mice were treated with 50 mg/kg/day of berberine chloride (n = 7, 5 females, 2 males) for 30 days. Both conditions share common pathophysiological pathways including abnormal lipid metabolism and inflammation. Recent studies have begun to investigate the impact of berberine on liver function. Jan 10, 2024 · The results suggest that berberine has positive effects on blood lipids, blood glucose, liver function, insulin resistance, and fatty liver condition in NAFLD patients. And you should always take a beat to According to 2014 research published in Biochemistry and Cell Biology, berberine may be a good option for the treatment of diabetes in those who are unable to use current anti-diabetes medications due to kidney problems, liver failure, or heart disease . But does Berberine Synergy really work as it claims? Well, let’s find out. So far, no approved pharmacological therapy for NAFLD h … Dec 14, 2023 · Studies have shown that berberine can help lower liver enzyme levels, indicating improved liver function. Located in the upper right part of the abdomen, the liver is responsible for a wide range of essential functions, including the metabolism of nutrients, the production of bile for digestion, the storage of vitamins and minerals, and the detoxification of harmful substances from the body. com FREE SHIPPING on qualified orders Jan 26, 2025 · Berberine’s possible benefits for cholesterol “Berberine has been shown to decrease total cholesterol, triglycerides and LDL cholesterol,” Dr. Common synergistic combinations include: Hydrogen-dominant SIBO: Berberine paired with Neem and Oregano. In the study of Yan et al. , RDN, LD, a registered dietitian with Mayo Clinic, thinks the term “nature’s Ozempic” for berberine is good marketing — but not necessarily honest or helpful. Here are some findings: Jan 11, 2024 · First, let's address liver health. Feb 17, 2025 · It uses natural ingredients like silymarin and berberine, known for supporting liver function and fat burning. What is berberine tea good for? Berberine has an impressive number of health benefits. Once-through … Jun 10, 2024 · 8. In addition to lowering liver fat levels, which is a precursor to non-alcoholic fatty liver disease (NAFLD), berberine has also been found to reduce liver fibrosis—a buildup of scar tissue in the liver that leads to Aug 12, 2024 · In addition, berberine stops the liver from making too much glucose. Lowers Cholesterol & Triglycerides. May 25, 2017 at 12:23 pm. But long-term use has not been studied and some animal studies report some severe side effects with long-term berberine use like enlarged liver/kidneys, muscle tremors, and gastric ulcers," Megan Hilbert, MS, RDN, a registered dietitian specializing in gut health nutrition at Top Nutrition Coaching, told Verywell in an email. com Oct 31, 2024 · Berberine offers potential benefits in supporting liver metabolism and enzyme activity, contributing to overall liver function. Aug 23, 2022 · The incidence of Non-Alcoholic Fatty Liver Disease (NAFLD) has been rapidly increasing during the last decade. liver failure, Does berberine kill good bacteria? Milk Thistle, known for its liver-protective properties, helps detoxify and regenerate liver cells, making it an essential herb for supporting liver function. 1 Direct Effects of Berberine on Liver Fibrosis. However, studies have also shown that it may also be good for liver health specifically. Overall there’s good research that berberine may be helpful for fatty liver disease. Research suggests that it may have Oct 13, 2024 · Berberine is also typically combined with other herbs for effective SIBO treatment. May protect the liver. Berberine does not damage the liver if used in moderation and/or as recommended by a healthcare professional. Yet some research has revealed that berberine may have negative effects on the liver. Sep 1, 2022 · Berberine is a plant alkaloid to which antihyperglycemic properties have been attributed. nlm. [16] The pancreas is a glandular organ with endocrine and exocrine functions necessary for the maintenance of blood glucose homeostasis and secretion of digestive enzymes. Here, we investigated the aspects and extent to which glucolipid metabolism were Keywords: Nonalcoholic Fatty Liver Disease, Berberine, Liver Enzymes, FBS, Lipid Profiles. How Can Berberine Help? Exactly how berberine can be of benefit to people is still under some investigation. Berberine supports liver function by reducing fat accumulation and improving lipid metabolism. In fact, it has been shown to decrease waist circumference and waist-to-hip ratio. Berberine’s effect on glucose uptake, insulin sensitivity, and how the liver works makes it a strong option for diabetes management. Oct 17, 2023 · According to a comprehensive review published in early 2023, berberine plays an effective role as an antioxidant, anti-inflammatory, and anti-cancer agent while helping to protect the liver and cardiovascular systems. (2014) revealed that berberine significantly reduced oxidative stress markers and inflammatory cytokines in a CKD rat model. McCoy says, is no Americans surveyed who had advanced or end-stage kidney disease took supplements flagged as potentially risky by the National Kidney Foundation. Jun 2, 2023 · Berberine has been used in traditional medicine for centuries, and now berberine supplements are popular as a natural aid for people with type 2 diabetes, high cholesterol, high blood pressure Sep 19, 2024 · BBR exacerbated liver inflammation and fibrosis specifically in Pi*Z mice. Aug 8, 2023 · Studies have shown that berberine supplementation can lead to improvements in liver fat content, liver enzyme levels, and insulin sensitivity in individuals with NAFLD. However, further research involving larger human trials is necessary to strengthen these findings and ascertain the full scope of berberine’s effects on liver health. Most berberine supplements come in capsules, however, and may use vegetable casings of any color. After filtering out low-quality cells based on defined thresholds (200 BBR treatment did not reduce the PAS-D positive globules in the liver, and the severity of liver inflammation was correlated with the percentage of the PAS-D positive globules in the liver section. Methods This study was registered with Oct 6, 2020 · Berberine is a quaternary ammonia compound found in many botanical products, including goldenseal, barberry and Oregon grape, which is used for its purported antioxidant and antimicrobial properties for a host of conditions, including obesity, diabetes, hyperlipidemia, heart failure, H. Ed. Good for the lung but bad for the liver? Garlic-induced hepatotoxicity following liver transplantation. 2015 , it was found that, compared with lifestyle intervention group, berberine could significantly lower liver lipid content in patients with NAFLD; in the study of Xie et al. Nov 18, 2024 · 3. Berberine is an herbal extract with a number of research-proven benefits to metabolism. The National Library of Medicine adds that, based on scientific evidence, berberine might be effective for treating: Oct 25, 2024 · Citation 5–7 Liver fibrosis is currently being treated by protecting normal liver cells, Citation 8 inhibiting hepatic stellate cells (HSCs) activation, Citation 9 decreasing extracellular matrix synthesis and secretion, Citation 10 and reducing liver inflammation. Liver Health and Nonalcoholic Fatty Liver Disease (NAFLD) Nonalcoholic fatty liver disease (NAFLD) is a growing health concern linked to obesity and insulin resistance. These reach the liver through the portal vein, too. Jun 19, 2023 · Be especially cautious if you take drugs that interact with the liver. Berberine can improve insulin sensitivity and promote the absorption of sugar into cells. Side effects of berberine. "I recommend berberine to most of my patients with diabetes, arthritis and even heart disease," he notes. Dec 19, 2024 · Atherosclerosis (AS) and Non-alcoholic fatty liver disease (NAFLD) are chronic metabolic disorders with high prevalence and significant health impacts. A total of 184 eligible patients with NAFLD were enrolled and randomly received (i . Antimicrobial properties: Berberine has been used for centuries in traditional medicine for its antimicrobial properties. Sep 30, 2019 · The good news, Dr. Blood fats: Berberine lowered bad fats and raised good cholesterol. We recommend getting your liver function tests (liver enzymes) every 6 months. Cirrhosis occurs when there is a large amount of scar tissue (fibrosis) inside the liver. Natural compounds, such as berberine (BBR) and quercetin (QR), have shown the ability to regulate energy metabolism and protect the liver without significant adverse effects. BBR is converted to dihydroberberine (dhBBR) and other metabolites by the action of nitroreductase or specific intestinal microorganisms. This recent study showed that berberine significantly reduced liver inflammation, fibrosis, and lipid peroxides (oxidation of fat within the liver). Jan 5, 2021 · Liver plays an important role in bile synthesis, metabolic function, degradation of toxins, new substances synthesis in body. This study implicates that BBR should be avoided by AATD patients. Research suggests that berberine can reduce liver fat content, which could have a positive effect on those with NAFLD. 2011 , it was found that the obvious effect rate was 70% after treatment with berberine via liver type-B ultrasonic examination, and there was Sep 1, 2022 · Berberine is a plant alkaloid to which antihyperglycemic properties have been attributed. Liver diseases have a wide prevalence globally and the fifth most common cause of death among all gastrointe … The real danger though, lies in the potential for fatty liver to progress to cirrhosis of the liver. Mar 5, 2025 · “Berberine does appear to be safe for adults to use in the short term. Most evidence suggests that berberine may be protective rather than harmful to the liver. Results: Berberine significantly improved HFFGD-induced weight gain, hepatic lipid accumulation and increases in serum liver enzymes, thereby alleviating NAFLD. Methods A randomized, parallel controlled, open-label clinical trial was conducted in three medical centers (NIH Registration number: NCT00633282). Nov 22, 2024 · Last but not least, berberine has been shown to improve liver function, including reducing fatty liver (hepatic steatosis). The researchers suggested it may serve as a candidate anti-cancer agent for this common type of canine tumor. (2017). A study published in the Journal of Clinical Endocrinology and Metabolism found that berberine could significantly reduce levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST), two enzymes commonly used to assess Aug 23, 2023 · Berberine alters the gut microbiota environment in mice with alcoholic liver disease treated with BBR (10, 50, 100 mg/kg) by gavage, decreases the abundance of Pseudoflavonifractor, Mucisirillum, Alistipes, Ruminiclostridium, and Lachnoclostridium and increases the abundance of Akkermansia muciniphila. Studies have shown berberine can help lower blood sugar and cholesterol, and it even makes weight loss easier. Berberine may also help improve HDL cholesterol levels, so it may support heart health from that side as well. Berberine has not been linked to serum aminotransferase Mar 8, 2025 · 5. Nov 22, 2024 · Research supports berberine’s ability to promote liver health, particularly by improving lipid metabolism and reducing fat accumulation in the liver. 5%) patients suffered from transient gastrointestinal adverse effects. Schmidt, M. It fights bad stuff in your body, makes swelling go away, and helps insulin work right. Jun 9, 2023 · Tara A. Now, let’s discuss another aspect of berberine worth considering—its potential impact on liver health. In this review, we’ll take a closer look at Berberine Synergy’s formulation, effectiveness, benefits, customer feedback, and potential drawbacks. Thus, BBR might exert its therapeutic effect on NAFLD by improving glucolipid metabolism. NAFLD involves an extensive array of clinical conditions. Feb 23, 2025 · In studies, berberine helped improve ovulation by an average of 25% for women who had irregular menses. Berberine vs. Berberine treatment significantly improved insulin resistance in NAFLD rats by up-regulating IRS-2 mRNA and protein levels, suggesting its potential as a treatment for NAFLD. It is also known as an inhibitor of mitochondrial functions. Feb 28, 2025 · Liver fibrosis, caused by chronic hepatic injury, is a major threat to human health worldwide, as there are no specific drugs available for its treatment. “That may mean that awareness translates to caution or to greater odds of discussing supplement use with their clinical team,” she says. Liver scRNA-seq data were obtained from the GEO dataset GSE115469 (platform: GPL16791, primary liver samples from 5 patients), and aortic scRNA-seq data from the GEO dataset GSE260657 (platform: GPL21290, including samples from 7 asymptomatic patients and 8 AS patients). Berberine is a chemical found in some plants like European barberry, goldenseal, goldthread, Oregon grape, phellodendron, and tree turmeric. Lower levels suggest better liver function. Dec 21, 2024 · The liver is responsible for detoxification and metabolism, making it a critical organ for overall health. Schatz said. In this work short-term translation of the latter effects on hepatic metabolism were investigated using the isolated perfused rat liver. Apr 29, 2021 · Buy Milk Thistle Liver Support Supplement - Herbal Liver Supplement with Silymarin Milk Thistle Extract Dandelion Root Artichoke Extract Choline Bitartrate Berberine and Chicory Root for Liver Cleanse on Amazon. Research on Berberine and Liver Health. Mar 1, 2024 · Background Non-alcoholic fatty liver disease (NAFLD) is becoming increasingly prevalent worldwide, emerging as a significant health issue on a global scale. Mar 28, 2023 · Angela Grassi. Aug 7, 2015 · Objectives A randomized, parallel controlled, open-label clinical trial was conducted to evaluate the effect of a botanic compound berberine (BBR) on NAFLD. When combined with TUDCA, which offers additional benefits such as promoting healthy bile flow and protecting against liver damage, these supplements create a potent duo for enhancing Nov 29, 2024 · A study investigated the molecular mechanism and therapeutic potential of berberine in nonalcoholic fatty liver disease (NAFLD). It is especially beneficial for type 2 diabetics. Many however are interested in its weight loss properties. Berberine for diabetes: effect on blood sugar. It may also be linked to other benefits and could aid in the treatment of conditions Apr 10, 2023 · Berberine was reported to be protective against various types of liver disease, particularly nonalcoholic fatty liver disease, in one research. Lowering your weight and cholesterol can reverse fatty liver disease. Oct 30, 2021 · Dr. It may help prevent or manage non-alcoholic fatty liver disease (NAFLD) by lowering triglyceride levels and reducing oxidative stress within liver cells. Berberine is a bitter-tasting and yellow-colored chemical. Preventing liver exposure to damage factors and good lifestyles are the most effective approaches (Bédossa and Paradis, 2003), but patient compliance is very poor. Berberine (BBR), an isoquinoline alkaloid, is known for its beneficial effects on various metabolic and cardiovascular disorders May 10, 2024 · … Berberine, an isoquinoline alkaloid derived from plants of the generis Berberis, has been recognized as being capable of decreasing oxidative stress, LDL, triglycerides, and insulin resistance and of improving the mood. Functional liver or kidney damages were not observed for all patients. Dec 17, 2024 · While berberine is generally safe for most people, certain groups should avoid it or use it with caution, including pregnant and breastfeeding women, children, people with low blood pressure, individuals with liver or kidney diseases, as well as people taking certain medications (refer to the section ‘is berberine safe). especially in individuals having pre-existing liver conditions. Others claim that it is good for mental health and can even prevent fatty liver disease. Fratellone says he has used berberine plants to treat urinary tract infections and that it is also commonly used for GI problems, circulatory issues, liver diseases and bronchial ailments. Jan 27, 2025 · Reducing cholesterol levels: It has been shown to lower LDL cholesterol (‘bad cholesterol’) and triglyceride levels, while simultaneously increasing HDL cholesterol (‘good cholesterol’). This interaction can either enhance or diminish the effectiveness of certain drugs. Meanwhile, our gut bacteria make substances called metabolites that are good for the liver 9. However, if you have health issues or allergies, it’s a good idea to talk to your doctor before starting Liv Pure . Berberine can make some medicines less effective. However, there are some studies that indicates potential negative effects of berberine on the liver if consumed in excess and for a prolonged period of time, such as liver stress and rise in the levels of liver enzymes. Berberine is good for your gut, but Mar 1, 2022 · 4. ncbi. It has been shown to possess potent anti-inflammatory, anti-microbial, anti-cancer, and anti-aging properties. One of the most promising is Berberine (BBR). These findings suggest that berberine can alleviate the inflammatory and oxidative burden in CKD patients. dhBBR, other metabolites and unmetabolised pro-BBR in turn act on intestinal flora (such as anaerobes) to regulate the microorganism Feb 27, 2025 · No. See full list on liverdoctor. Berberine (BBR), an active ingredient from nature plants, has demonstrated multiple biological activities and pharmacological effects in a series of metabolic diseases including nonalcoholic fatty liver disease (NAFLD). Today, berberine gets high marks for its natural pharmacological properties, including its health-supportive effects on the immune system, metabolism Jun 1, 2022 · All titles and abstracts were screened to evaluate eligibility for inclusion. This review describes the cellular and clinical effects associated with the use of berberine, which suggest that this molecule could be an effective […] May 28, 2020 · Is berberine good for your liver? If you guessed yes, you are correct! Berberine has numerous mechanisms by which it may help protect the liver, particularly against NAFLD (non-alcoholic fatty liver disease). However， several recent studies have shown that berberine can exert a therapeutic effect on the diseases such as autoimmune hepatitis， viral hepatitis， nonalcoholic fatty Mar 24, 2024 · Liver Fibrosis and Cirrhosis: Preclinical studies have shown that berberine prevents hepatic fibrosis progression, reverses established fibrosis, and promotes liver regeneration in animal models Oct 5, 2024 · Monitoring liver function during berberine use is recommended to mitigate risks of drug-induced liver injury, although substantial evidence linking berberine to significant liver injury is lacking. Hydrogen and Methane-dominant SIBO : Berberine paired with Allicin (from garlic). This is attributed to its anti-inflammatory and anti-oxidative properties. In fact there is ongoing research to confirm that when taken in the right dosage, berberine may actually be beneficial at restoring the liver if there has been damage caused by non-alcoholic fatty liver disease. We would like to show you a description here but the site won’t allow us. Consulting a healthcare provider ensures that berberine supplementation is safe and appropriate for individual health needs. Is berberine good for the liver? Although more research is needed to confirm it can defend against liver diseases, early research suggests that berberine supports the liver by decreasing blood sugar, insulin resistance and triglycerides, which are markers of liver damage in people with diabetes and viruses like hepatitis. Its pleiotropic effect positively impacts various cardiometabolic aspects. Sep 12, 2024 · Shaikh SA, et al. Traditional Diabetes Medications Feb 3, 2025 · Berberine seems to help liver function by directly affecting the liver, and also through its effect on cholesterol and weight. Jan 29, 2024 · Liver health: Berberine may support liver health by reducing liver fat accumulation, improving liver function, and protecting against liver-related diseases such as fatty liver disease. A study by Zhang et al. However, it is important to note that more rigorous clinical trials are necessary to determine the optimal dosage, duration, and long-term effects of berberine supplementation Berberine is particularly effective for people with syndrome X. By increasing the activity of LDL receptors in the liver, berberine enhances the clearance of LDL cholesterol from the body. Grace, Berberine with long-term use can increase the risk for liver damage. Berberine (BBR) exerts anti-hyperglycemic and anti-dyslipidemic effects and can also ameliorate NAFLD. It is a relevant health problem that affects 25% of the general population. These may include liver fibrosis, liver cirrhosis, and drug-induced liver toxicity. May 25, 2024 · Berberine is special because it's good for you in many ways. Berberine has demonstrated hepatoprotective effects in several studies. Jun 13, 2023 · In particular, berberine has been shown to lower blood sugar, increase weight loss, and improve heart health. ↑What is “already known” in this topic: Berberine is known as an antidiabetic, antiobesity, hypotensive, and hypolipidemic agent and is recommended as an effective intervention in non-alcoholic fatty liver and metabolic syndrome. Pancreatitis is characterized by inflammation of the pancreas leading to temporary Oct 13, 2023 · During the trial, 20 (34. Berberine exhibits potential for treating NAFLD, but clinical evidence remains inconclusive. While this side effect is relatively rare, it’s crucial to be aware, especially if you’re considering berberine as part of your wellness routine. In this review, we summarize NAFLD, its metabolic and cardiovascular complications, the hepatoprotective effects of BBR due to its broad spectrum of pharmacological effects, and the potential role of BBR in NAFLD therapy. May 26, 2024 · Berberine has been shown to possess potent anti-inflammatory and antioxidant properties. Berberine is well appreciated for its antidiabetic and lipid-balancing effects, both of which impact fatty liver changes. Feb 27, 2025 · A systematic review and meta-analysis published in the Journal of Translational Medicine found support for the efficacy of berberine in improving liver enzymes, insulin sensitivity, and lipid profile in people with non-alcoholic fatty liver disease. This means there is less glucose released into the bloodstream. The fundamental feature of liver fibrosis is the abnormal activation of HSCs, and BBR has been shown to be a potential treatment for thioacetamide (TAA)-, CCl 4-, ethanol- and high cholesterol-induced liver fibrosis models; in these contexts, it likely acts by suppressing HSC activation and downregulating alpha-smooth muscle actin (α-SMA) and Jan 5, 2021 · The high incidence of liver disease has become a major health concern, so a series of public interventions have been implemented to reduce the burden on liver. Berberine may interact with various medications due to its effect on liver enzymes responsible for drug metabolism. Another benefit of berberine seen in the early clinical trials is improvements in lipid profiles. Studies show Jan 27, 2025 · Berberine Synergy by Designs for Health claims to promote metabolic health and enhance cardiovascular and liver function. Feb 28, 2017 · Background Nonalcoholic fatty liver disease (NAFLD) is considered a critical hepatic manifestation of metabolic syndrome. nih. Berberine’s metabolic and anti-inflammatory properties may help: Reduce fat accumulation in the liver; Improve liver enzyme levels Sep 1, 2022 · In addition of being an important target of the hypoglycemic action of berberine, the liver is also the main organ responsible for its metabolism, and also the organ where berberine accumulates (Tan et al. Traditional Chinese medicine (TCM) has … Jun 20, 2024 · These reasons alone make berberine a substance that helps promote optimal health. This is particularly beneficial for individuals with non-alcoholic fatty liver disease (NAFLD), a condition characterized by excess fat in the Aug 18, 2023 · Preliminary findings indicate that berberine may positively impact liver function and support liver detoxification processes. Dec 28, 2024 · While these benefits are promising, it is crucial to consider the implications of berberine on liver health. Using Berberine for an effective SIBO Protocol The mice were administered berberine (300 mg/kg/d) by gavage, and fatty liver levels and bone loss indicators were tested. This is great for people with kidney disease, chronic kidney disease, or type 2 diabetes. Another study discovered that berberine medication could reverse liver damage caused by high dosages of acetaminophen. Additionally, combination therapy (the cocktail therapy approach Oct 20, 2023 · Berberine is a naturally occurring compound in goldenseal, Oregon grape, tree turmeric, and other plants. Feb 23, 2024 · Berberine is an antipyretic and detoxicating drug commonly used in clinical practice， and it is currently used for the routine treatment of gastrointestinal diseases such as bacterial gastroenteritis and diarrhea. https://pubmed. Berberine increased trabecular number (Tb. This meta-analysis was conducted to assess the efficacy and safety of berberine for treating NAFLD. Although research suggests some good uses for berberine, it’s not ready for prime time as an obesity treatment. Aug 29, 2024 · Studies show that it helps your body respond better to insulin and prevents your liver from creating more glucose. In human studies, berberine has shown promise against a variety of cancer types, including breast, colorectal, liver, and prostate cancer. For a study to be included in the systematic review, it had to be a) RCTs with either parallel or cross-over design, b) participants aged 18 years or older, c) intervention with berberis aristate/Silybum marianum, d) assessment of liver enzymes. Introduction. Since the liver is also the organ that metabolizes drugs, it bears the brunt of consistent use of acetaminophen. Weight loss: Using berberine may reduce belly fat for people with PCOS who have a hard time losing weight due to their condition. The real danger though, lies in the potential for fatty liver to progress to cirrhosis of the liver. Impact on liver health. ybgawwlmryamvglltjbqqkcvyrcqhuwydatjwxihnukzlkxxfqaadsnagfvtwwnpvh